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Hocane was born in Karachi but she grew up in Islamabad where she completed her education from Bahria College, Islamabad. She is the sister of another television actress Mawra Hocane. As a teenager, she performed as a theater artist before she started working as a VJ for ARY Musik.
Hocane made her acting debut with leading role in the 2012 romantic drama Meri Ladli alongside Ahsan Khan and Sajal Ali. She later apeared in hit serial such as Kahi Un Kahi, and Madiha Maliha.Her portrayal of a girl subjected to family pressures and a forced wedding in Marasim gained her critical acclaim and recognition.
She made her film debut in the 2014 romantic comedy Na Maloom Afraad opposite Fahad Mustafa, Mohsin Abbas Haider and Javed Sheikh. The film received generally positive reviews, and she was praised for her performance.She was offered Ekta Kapoor’s Bollywood film Azhar alongside Emran Hashmi, which she refused saying that she don’t want to do bold scenes.